Diabetic Neuropathy Collection: Introduction to Diabetic Neuropathy

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Diabetic neuropathy.

Diabetic neuropathy affects up to 60 percent of the estimated 13 million Americans who have diabetes mellitus. Foot and ankle complications are responsible for more hospital admissions than all other complications of diabetes mellitus combined. Neuropathy is more likely to affect patients who have higher degrees of hyperglycemia and a longer history of diabetes, and those who are older, taller ...

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[Diabetic neuropathy].

Diabetic neuropathy, the most common peripheral neuropathy in the Western world, is responsible for most limb amputations and considerable morbidity in diabetic patients. Although it is a sequela to insulin deficiency and/or hyperglycemia, its exact pathogenetic mechanism remains unclear. Therapy is directed at early diagnosis, exclusion of other neuropathic disorders, prudent glucose control, ...

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[Diabetic neuropathy].

Better clinical characteristics and a standardized approach to the definition of neuropathy has enabled us to define more precisely the natural history of diabetic neuropathy. Detailed studies on the pathology and pathogenesis have allowed dissection of important pathogenetic pathways. Effective treatment is currently limited, although a number of new and potentially important therapeutic inter...

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Diabetic Neuropathy.

Peripheral nerve disorders are important late complications of diabetes mellitus. Polyneuropathy, which may involve varying proportions of sensory, motor, and autonomic fibers, is considered the consequence of metabolic derangements that result from chronic hyperglycemia. Symmetrical proximal motor neuropathy ("diabetic amyotrophy") also may have a metabolic basis. Mononeuropathies in diabetes ...

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Diabetic neuropathy.

Diabetes is the most common cause of peripheral neuropathy in the world. Both type 1 (insulin-dependent) and type 2 diabetes are commonly complicated by peripheral nerve disorders. Two main types of neuropathy are observed: the most common is a nerve fiber length-dependent, distal symmetrical sensory polyneuropathy with little motor involvement but frequent, and potentially life threatening, au...

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ژورنال

عنوان ژورنال: Diabetes Therapy

سال: 2020

ISSN: 1869-6953,1869-6961

DOI: 10.1007/s13300-020-00773-6